Tetrahedron Letters

CuO nano-particles supported on silica, a new catalyst for facile synthesis of benzimidazoles, benzothiazoles and benzoxazoles

SM Inamdar, VK More, SK Mandal

Index: Inamdar, Suleman M.; More, Vinod K.; Mandal, Sisir K. Tetrahedron Letters, 2013 , vol. 54, # 6 p. 579 - 583

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Citation Number: 52

Abstract

A facile synthetic route for benzimidazoles, benzothiazoles and benzoxazoles comprising the reaction of corresponding o-phenylenediamine, o-aminothiophenol and o-aminophenol with various aldehydes using silica supported nano-copper (II) oxide as a catalyst has been described. The catalyst exhibited a clean reaction profile with excellent yields in a short reaction time. The catalyst can be recycled effectively after use.