New aspects in the hydrogenolytic opening of 2-isoxazolines

S Auricchio, A Ricca

Index: Auricchio, Sergio; Ricca, Aldo Tetrahedron, 1987 , vol. 43, # 17 p. 3983 - 3986

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Citation Number: 14

Abstract

It has been observed that the hydrogenolytic opening of 2-isoxazolines depends on the substituents present in positions 3 and 5. The hydrogenolysis on 10% Pd/C of 2- isoxazolines, substituted in position 3 with carbonyl or carboxyl groups and in position 5 with an aromatic group, gives oximes, in contrast to other isoxazoline derivatives. From the 5-aryl- 2-isoxazolines it is possible to obtain aminoalcohols in ethanol and oximes in acetic acid.