Delaumonones A and B, new antiplasmodial quassinoids from Laumoniera bruceadelpha

S Oshimi, A Takasaki, Y Hirasawa, T Hosoya…

Index: Oshimi, Shiori; Takasaki, Aki; Hirasawa, Yusuke; Hosoya, Takahiro; Awang, Khalijah; Hadi, A. Hamid A.; Ekasari, Wiwied; Widyawaruyanti, Aty; Morita, Hiroshi Chemical and Pharmaceutical Bulletin, 2009 , vol. 57, # 8 p. 867 - 869

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Citation Number: 8

Abstract

New quassinoids, delaumonones A (1) and B (2) have been isolated from the bark of Laumoniera bruceadelpha NOOTEBOOM (Simaroubaceae) and the structures were elucidated by 2D NMR analysis and a chemical correlation. Delaumonones showed an antimalarial activity against Plasmodium falciparum.

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