A Biomimetic Synthesis of Benzo [c] Phenanthridine Alkaloid Nitidine

T Kametani, M Takemura, M Ihara…

Index: Kametani,T. et al. Israel Journal of Chemistry, 1977 , vol. 16, p. 4 - 6

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Citation Number: 4

Abstract

Abstract Oxidation of 1, 2, 3, 4-tetrahydro-7-hydroxy-6-methoxy-3-(4, 5-dimethoxy-2- vinylphenyl)-2-methylisoquinoline (10), derived from the corresponding berbine methiodide (8), with lead tetraacetate, followed by acidic treatments, gave 5, 6-dihydro-8-hydroxy-2, 3, 9- trimethoxy-5-methylbenzo [c] phenenthridine (20). By a similar procedure, 1, 2, 3, 4- tetrahydro-7-hydroxy-6-methoxy-3-(4, 5-methylenedioxy-2-vinylphenyl)-2- ...

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