Organic & biomolecular chemistry

Thio-arylglycosides with various aglycon para-substituents: A probe for studying chemical glycosylation reactions

X Li, L Huang, X Hu, X Huang

Index: Li, Xiaoning; Huang, Lijun; Hu, Xiche; Huang, Xuefei Organic and Biomolecular Chemistry, 2009 , vol. 7, # 1 p. 117 - 127

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Citation Number: 15

Abstract

Three series of thioglycosyl donors differing only in their respective aglycon substituents within each series have been prepared as representatives of typical glycosyl donors. The relative anomeric reactivities of these donors were quantified under competitive glycosylation conditions with various reaction time, promoters, solvents and acceptors. Over three orders of magnitude reactivity difference were generated by simple transformation of ...