General Synthesis Route to Benanomicin??Pradimicin Antibiotics

M Tamiya, K Ohmori, M Kitamura, H Kato…

Index: Kato; Ohmori; Suzuki Synlett, 2001 , # SPEC. ISS p. 1003 - 1005

Full Text: HTML

Citation Number: 24

Abstract

Abstract A general approach to the regio-and stereoselective total synthesis of the benanomicin-pradimicin antibiotics (BpAs) is described. Construction of the aglycon has been achieved by 1) the diastereoselective ring-opening of a biaryl lactone by using (R)-