Synthesis of Unsymmetrical Diphenylalkenes1

JF Miquel, H Wåhlstam, K Olsson…

Index: Miquel,J.-F. et al. Journal of Medicinal Chemistry, 1963 , vol. 6, p. 774 - 780

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Citation Number: 20

Abstract

1 2 3 4 acids weie prepaied hy the reaction of carboii dioxide with the corresponding Grigiiard reagent, according to the iiietliod of Ruzicka. l? The other acids were prepared by alkylating, hydrolyziug, and monoclecarboxylatiiig the maloiiic ester. l 3 The yield of dirnethoxyplieiiylethrleiie was hetween 50 and SO%, calculated oil the basis of the esters used. 111 110 case was isolation of the iiitei. niediate carbinol attempted, because, as is\ ...