Tetrahedron letters

Extension of the Willgerodt–Kindler reaction: protected carbonyl compounds as efficient substrates for this reaction

HR Darabi, K Aghapoor, M Tajbakhsh

Index: Darabi, Hossein Reza; Aghapoor, Kioumars; Tajbakhsh, Mahmoud Tetrahedron Letters, 2004 , vol. 45, # 21 p. 4167 - 4169

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Citation Number: 23

Abstract

Nitrogen derivatives of carbonyl compounds such as oximes, hydrazones, and semicarbazones were found to be excellent candidates for the Willgerodt–Kindler reaction. They can be used directly in a solvent-free reaction, under both classical and microwave conditions, to give the corresponding thiomorpholides in good yields.