Organic letters

Palladium-catalyzed arylation of cyanamides

RM Stolley, W Guo, J Louie

Index: Stolley, Ryan M.; Guo, Wenxing; Louie, Janis Organic Letters, 2012 , vol. 14, # 1 p. 322 - 325

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Citation Number: 11

Abstract

The cross-coupling of alkyl cyanamides with a number of aryl, heteroaryl, and vinyl halide and pseudohalide coupling partners has been developed via a modification of Pd-catalyzed amidation methods. The reactions proceed selectively under mild conditions with reasonable reaction times in moderate to excellent yields.