Synthesis and pharmacological characterization of [125I] iodomethyllycaconitine ([125I] Iodo-MLA). A new ligand for the α7 nicotinic acetylcholine receptor
HA Navarro, D Zhong, P Abraham, H Xu…
Index: Navarro, Hernan A.; Zhong, Desong; Abraham, Philip; Xu, Heng; Carroll, F. Ivy Journal of Medicinal Chemistry, 2000 , vol. 43, # 2 p. 142 - 145
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Citation Number: 31
Abstract
Since the nicotinic acetylcholine receptors (nAChRs) have been targeted for the development of drugs for cognitive function, Parkinson's disease, analgesia, inflammatory bowel disorder, schizophrenia, anxiety, depression, Tourette's syndrome, and smoking cessation, considerable effort has been directed toward the identification and characterization of radioligands for this receptor system. 1, 2 Two major classes of ...
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