A Practical Procedure for the Synthesis of Esonarimod,(R, S)-2-Acetylthiomethyl-4-(4-methylphenyl)-4-oxobutanoic Acid, an Antirheumatic Agent.(Part 1).

T Noguchi, A Onodera, K Tomisawa…

Index: Chemical and pharmaceutical bulletin, , vol. 50, # 10 p. 1407 - 1412

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Abstract

... Key words esonarimod; antirheumatic drug; Friedel–Crafts acylation; Michael addition; process chemistry ... Kamiyama H., Yokomori S., The 121th An- nual Meeting of the Pharmaceutical Society of ... 17) Toyama Chemical Co., Ltd., 3–2–5 Nishishinjuku, Shinjuku-ku, Tokyo, Japan. ...

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[Montanaro, Sara; Ravelli, Davide; Merli, Daniele; Fagnoni, Maurizio; Albini, Angelo Organic Letters, 2012 , vol. 14, # 16 p. 4218 - 4221]

A Practical Procedure for the Synthesis of Esonarimod,(R, S)-2-Acetylthiomethyl-4-(4-methylphenyl)-4-oxobutanoic Acid, an Antirheumatic Agent.(Part 1).

[Noguchi, Toshiya; Onodera, Akira; Tomisawa, Kazuyuki; Yokomori, Sadakazu Chemical and pharmaceutical bulletin, 2002 , vol. 50, # 10 p. 1407 - 1412]

A Practical Procedure for the Synthesis of Esonarimod,(R, S)-2-Acetylthiomethyl-4-(4-methylphenyl)-4-oxobutanoic Acid, an Antirheumatic Agent.(Part 1).

Abstract

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