Chemistry Letters

SYNTHESIS OF β, γ-UNSATURATE CARBOXYLIC ACID DERIVATIVES BY THE NOVEL Ni (CO) 4-INDUCED RING-OPENING CARBONYLATION REACTION OF 1, 1 …

T Hirao, S Nagata, T Agawa

Index: Hirao, Toshikazu; Nagata, Shinichiro; Agawa, Toshio Chemistry Letters, 1985 , p. 1625 - 1628

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Citation Number: 4

Abstract

1, 1-Dibromo-2-chlorocyclopropanes underwent the Ni (CO) 4-induced ring-opening carbonylation reaction with alcohol or amine giving the β, γ,-unsaturated carboxylic acid and dicarboxylic acid derivatives. Use of N, N-dimethyltrimethylsilylamine as an initial nucleophile in the presence of benzaldehyde led to a dienecarboxamide presumably via codensation of the nickel enolate intermediate.