Oxidation of diclofenac sodium by diperiodatoargantate (III) in aqueous alkaline medium and its determination in urine and blood by kinetic methods

…, SA Chimatadar, ST Nandibewoor

Index: Naik; Chimatadar; Nandibewoor International Journal of Chemical Kinetics, 2010 , vol. 42, # 6 p. 336 - 346

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Citation Number: 3

Abstract

Abstract The kinetics and oxidation of diclofenac sodium (DFS) by diperiodatoargentate (III)(DPA) in alkaline medium at 298 K and at a constant ionic strength of 0.60 mol dm− 3 were studied spectrophotometrically. The oxidation products were [2-(2, 6-dicloro- phynylamino)-phenyl]-methenol and Ag (I), identified by LC-ESI-MS and IR spectral studies. The reaction between DFS and DPA in alkaline medium exhibits 1: 1 stoichiometry. The ...