Radical phosphination of organic halides and alkyl imidazole-1-carbothioates

A Sato, H Yorimitsu, K Oshima

Index: Sato, Akinori; Yorimitsu, Hideki; Oshima, Koichiro Journal of the American Chemical Society, 2006 , vol. 128, # 13 p. 4240 - 4241

Full Text: HTML

Citation Number: 32

Abstract

A wide range of aryl iodides 1 were subjected to the phosphination reaction (Table 1). Sterically demanding mesityl iodide (1d) was also phosphinated in good yield (entry 4). Functional groups such as ester, bromo, cyano, and keto moieties were compatible under the reaction conditions (entries 10−13). The radical conditions allowed for efficient phosphination of 4-iodophenyl triflate (1n) and allyl 4-iodobenzoate (1o), the transition metal-catalyzed phosphination of which ...