Spectral characterization of novel 3-phenyl-2-substituted quinazoline and fused quinazoline derivatives
…, WSI Abou-Elmagd, SS Abdelwahab…
Index: Mahmoud, Mahmoud R.; Abou-Elmagd, Wael S. I.; Abdelwahab, Salwa S.; Soliman, El-Sayed A. Synthetic Communications, 2013 , vol. 43, # 11 p. 1484 - 1490
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Citation Number: 5
Abstract
3-phenyl-2-thioxo-quinazolin-4(3H)one 1 was utilized for the construction of some novel 2-substituted quinazolin-4(3H)one derivatives through the formation of 2-hydrazinyl quinazolinone, which was used as the key starting material for the synthesis of 2-heteryl quinazolines via the reaction with one carbon donors, β-diketones and β-ketoester. Infrared, 1 H NMR, and mass spectra of the synthesized compounds were discussed. Some of them showed promising anti- ...
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