European Journal of Organic Chemistry

Dichotomous Reactivity in the Reaction of Triethyl??and Triphenylphosphane HBr Salts with Dimethyl Acetals: A Novel Entry to α??Alkoxy??Functionalized Ylides and …

P Das, J McNulty

Index: Das, Priyabrata; McNulty, James European Journal of Organic Chemistry, 2010 , # 19 p. 3587 - 3591

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Citation Number: 8

Abstract

Abstract The discovery of dichotomous reactivity in the reaction of trialkyl-vs. triphenylphosphane HBr salts with acetals allows entry to functionalized α-methoxy phosphonium salts and a novel process for tertiary phosphane methylation. The new protocol opens a general entry to the synthesis of vinyl ethers and differentially substituted 1, 3-dienes via Wittig reactions of the functionalized ylides derived from the α-methoxy ...

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