Tetrahedron

One-pot stibine modified Co 2 (CO) 8 catalyzed reductive N-alkylation of primary amides with carbonyl compounds

L Rubio-Pérez, P Sharma, FJ Pérez-Flores, L Velasco…

Index: Rubio-Perez, Laura; Sharma, Pankaj; Perez-Flores, F. Javier; Velasco, Luis; Arias, J. Luis.; Cabrera, Armando Tetrahedron, 2012 , vol. 68, # 10 p. 2342 - 2348

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Citation Number: 14

Abstract

A one-pot stibine modified Co2 (CO) 8 homogeneous catalytic reductive N-alkylation of primary amides using aldehydes/ketones as alkylating agents, is reported. Good to excellent yields of a wide range of secondary amides are obtained (up to 97%) under relative mild conditions.

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