Tetrahedron Letters

Synthesis of α-allenic aldehydes and allenyl trimethylsilyl ketones via (trimethylsilyloxy) butatrienes

RG Visser, L Brandsma, HJT Bos

Index: Visser, R. G.; Brandsma, L.; Bos, H. J. T. Tetrahedron Letters, 1981 , vol. 22, # 29 p. 2827 - 2828

Full Text: HTML

Citation Number: 16

Abstract

Abstract α-Lithiated (trimethylsilyloxy) butatrienes, generated by 1, 4-elimination of methanol from 1-trimethylsilyloxy-4-methoxy-2-alkynes with tert-butyllithium, give mixtures of α-allenic aldehydes and allenyl trimethylsilyl ketones which can be separated by distillation. The ratio aldehyde/ketone is solvent dependent.