One??Pot Synthesis of Benzofuryl??Substituted Semicarbazides Under Microwave Irradiation

XC Wang, LQ Chai, MG Wang, ZQ Quan…

Index: Wang, Xi-Cun; Chai, Lan-Qin; Wang, Man-Gang; Quan, Zheng-Qun; Li, Zheng Synthetic Communications, 2006 , vol. 36, # 5 p. 645 - 652

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Citation Number: 9

Abstract

Abstract A series of asymmetric semicarbazides was synthesized by reactions of 2?? benzofuran isocyanate, which was prepared by Curtius rearrangement from 2??benzofuroyl azide with acid hydrazide under microwave irradiation using a one??pot procedure. Comparing to the conventional method, this method has the advantages of mild conditions, easy handling, and high yield.