Synthesis

Carboxylate derivatives of oligopyridines bearing bromomethyl groups

S Bedel, G Ulrich, C Picard, P Tisnes

Index: Bedel, Sebastien; Ulrich, Gilles; Picard, Claude; Tisnes, Pierre Synthesis, 2002 , # 11 p. 1564 - 1570

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Citation Number: 9

Abstract

Abstract The synthesis of various oligopyridines possessing a carboxylate and at least one bromoethyl group is reported. The bipyridine and terpyridine cores were constructed in good yields via a Stille cross-coupling, starting from bromopicolines and ethyl bromopicolinate. The bromomethyl function was obtained by free radical bromination using NBS in benzene or bromine in benzene/water biphasic mixture. The building of two model podands by ...

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