Scaffold diversity through intramolecular cascade reactions of solid-supported cyclic N-acyliminium intermediates

ST Le Quement, TE Nielsen…

Index: Gu, Xuyuan; Ying, Jinfa; Agnes, Richard S.; Navratilova, Edita; Davis, Peg; Stahl, Gannon; Porreca, Frank; Yamamura, Henry I.; Hruby, Victor J. Organic Letters, 2004 , vol. 6, # 19 p. 3285 - 3288

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Citation Number: 40

Abstract

... J. Comb ... are highly reactive and transformed further in intramolecular cascade reactions with strong as well as weak C, N, S, and O ... was illustrated by installing a tyrosine residue, thus forming enkephalin analogue 15 with a constrained core previously suggested by Hruby and co ...