Synthesis and In Vitro Evaluation of 3??(1??Azolylmethyl)??1H??indoles and 3??(1??Azolyl??1??phenylmethyl)??1H??indoles as Inhibitors of P450 arom

ML Borgne, P Marchand, M Duflos…

Index: Archiv der Pharmazie, , vol. 330, # 5 p. 141 - 145

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Citation Number: 54

Abstract

... were prepared as follows: alkylation, aroylation, reduction into alcohol and azole introduction (Scheme 3). N-alkylation of 5-bromo- 1H ... Cpd Methoda Yield M p , T Formulab MS [%I solvent Mr (El7 9 c ... 312 methanol 38 1.27 139-141 CI ~ HI ~ BICIN ~ 415 (6). 348 methanol 415.72 ...