Synthesis and antibacterial evaluation of some theophylline derivatives

K Rathore, R Vyas, GL Talesara

Index: Rathore, Kavita; Vyas, Ritu; Talesara Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005 , vol. 44, # 10 p. 2166 - 2170

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Citation Number: 2

Abstract

Abstract: Some novel antiasthmatic theophylline derivatives have been synthesized and evaluated for biological activity. Oxygen substituted hydroxylamine compounds have been found to possess versatile pharmacological activities. Theophylline N-alkoxyarylbiguanides 8a-d have been prepared by condensing corresponding N-alkoxyamine salt 6a-c with substituted aryldicyandiamide 7, which in turn is prepared by Gabriel hydrolysis of ...