Asian Journal of Chemistry

A Facile, Chemoselective and Eco-friendly Solid Phase Synthesis of Enaminones Catalyzed by L-Proline

RS Bhupathi, BR Devi, PK Dubey

Index: Bhupathi, Raja S.; Devi, B.Rama; Dubey Asian Journal of Chemistry, 2011 , vol. 23, # 12 p. 5521 - 5524

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Abstract

Abstract A facile and chemoselective method for the synthesis of enaminones by the reaction of aromatic primary amines with various β-ketoesters in the presence of L-proline as activator under solid phase is described. The reactions are promoted by the catalyst in short time (5-6 min) under ambient conditions, without any side products.