Tetrahedron Letters

N-(Phenylselenomethyl) phthalimide as new reagent for mild protection of alcohols as Pim-ethers

A Temperini, L Minuti

Index: Temperini, Andrea; Minuti, Lucio Tetrahedron Letters, 2012 , vol. 53, # 22 p. 2709 - 2711

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Citation Number: 3

Abstract

A mild activation of N-(phenylselenomethyl) phthalimide by iodonium ion in the presence of alcohols to give the corresponding O-phthalimidomethyl derivatives (Pim-ethers) is provided. Simple cleavage of the phthalimido group with ethylenediamine is also reported thus making this approach a new and efficient method of protecting alcohols.

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