An Enantioselective Synthesis of (2 S, 3 R)-3-(N-Benzyloxycarbonyl) amino-1-chloro-4-phenylthiobutan-2-ol, a Central Intermediate of Nelfinavir1

M Ikunaka, J Matsumoto, Y Fujima…

Index: Organic Process Research and Development, , vol. 6, # 1 p. 49 - 53

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Citation Number: 15

Abstract

... Organic Process Research & Development. ... Research and Development ... However, the recent outbreak of an AIDS epidemic in developing countries has put anti-HIV drugs under severe price pressure 14 and made launching their new manufacturing processes less attractive. ...