Molecules

Synthesis and SAR studies of praziquantel derivatives with activity against Schistosoma japonicum

…, LJ Song, X Chen, XR Yin, WH Fan, GP Wang, CX Yu…

Index: Wang, Wen-Long; Song, Li-Jun; Chen, Xia; Yin, Xu-Ren; Fan, Wen-Hua; Wang, Gu-Ping; Yu, Chuan-Xin; Feng, Bainian Molecules, 2013 , vol. 18, # 8 p. 9163 - 9178

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Citation Number: 4

Abstract

Abstract: The synthesis and structure-activity relationship (SAR) studies of praziquantel derivatives with activity against adult Schistosoma japonicum are described. Several of them showed better worm killing activity than praziquantel and could serve as leads for further optimization.