Bulletin of the Chemical Society of Japan

The Mechanism of Fries Rearrangement and Acylation Reaction in Polyphosphoric Acid.

H Sharghi, H Eshghi

Index: Sharghi, Hashem; Eshghi, Hossien Bulletin of the Chemical Society of Japan, 1993 , vol. 66, # 1 p. 135 - 139

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Citation Number: 23

Abstract

Acylation reaction of m-cresol with 2-chlorobenzoic acid in PPA occurred through a prior esterification, followed by a Fries rearrangement of ester (3) to give benzophenones 4—7. Ester 3 undergoes the Fries rearrangement in PPA, giving benzophenones 4—7 in about the same yield as can be obtained by direct acylation reaction of m-cresol with 2- chlorobenzoic acid. The benzophenone 5 is not stable in PPA and decomposed to ...