Process research and scale-up of a commercialisable route to maraviroc (UK-427,857), a CCR-5 receptor antagonist
J Åhman, M Birch…
Index: Soai; Oyamada; Takase Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 8 p. 2327 - 2328
Full Text: HTML
Citation Number: 23
Abstract
... 1113. DOI: 10.1021/op800062d. Publication Date (Web): October 4, 2008. Copyright © 2008 American Chemical Society. ... figure Scheme 3. Chemical research and development a. ... The process safety evaluation of this chemistry determined the maximum rate of hydrogen evolution ...
Related Articles:
A simple method for the reduction of carboxylic acids to aldehydes or alcohols using H2 and Pd/C
[Falorni, Massimo; Giacomelli, Giampaolo; Porcheddu, Andrea; Taddei, Maurizio Journal of Organic Chemistry, 1999 , vol. 64, # 24 p. 8962 - 8964]
Synthesis and binding properties of guanidinium biscarboxylates
[Spaeth, Andreas; Gonschor, Janina; Koenig, Burkhard Monatshefte fur Chemie, 2011 , vol. 142, # 12 p. 1289 - 1308]
[Srivastava, Tumul; Srivastava, Tushar K.; Haq; Katti, Seturam B. Journal of Chemical Research - Part S, 2003 , # 8 p. 516 - 517]
Anaerobic nitroxide-catalyzed oxidation of alcohols using the NO+/NO· redox pair
[Holan, Martin; Jahn, Ullrich Organic Letters, 2014 , vol. 16, # 1 p. 58 - 61]
[Camplo; Niddam; Barthelemy; Faury; Mourier; Simon; Charvet; Trabaud; Graciet; Chermann; Kraus European Journal of Medicinal Chemistry, 1995 , vol. 30, # 10 p. 789 - 800]