Structure and thermotropic phase behavior of a homologous series of bioactive N-acyldopamines

ST Reddy, PK Tarafdar, RK Kamlekar…

Index: Reddy, S. Thirupathi; Tarafdar, Pradip K.; Kamlekar, Ravi Kanth; Swamy, Musti J. Journal of Physical Chemistry B, 2013 , vol. 117, # 29 p. 8747 - 8757

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Citation Number: 11

Abstract

N-Acyldopamines (NADAs), which are present in mammalian nervous tissues, exhibit interesting biological and pharmacological properties. In the present study, a homologous series of NADAs with varying acyl chains (n= 12–20) have been synthesized and characterized. Differential scanning calorimetric studies show that in the dry state the transition temperatures, enthalpies, and entropies of NADAs exhibit odd–even alternation ...