Iron-catalyzed cross-coupling reactions

A Fürstner, A Leitner, M Méndez…

Index: Fuerstner, Alois; Leitner, Andreas; Mendez, Maria; Krause, Helga Journal of the American Chemical Society, 2002 , vol. 124, # 46 p. 13856 - 13863

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Citation Number: 563

Abstract

Simple iron salts such as FeCl n, Fe (acac) n (n= 2, 3) or the salen complex 4 turned out to be highly efficient, cheap, toxicologically benign, and environmentally friendly precatalysts for a host of cross-coupling reactions of alkyl or aryl Grignard reagents, zincates, or organomanganese species with aryl and heteroaryl chlorides, triflates, and even tosylates. An “inorganic Grignard reagent” of the formal composition [Fe (MgX) 2] prepared in situ ...

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