Organic letters

Stereoselective Synthesis of Novel β, γ-Epoxyhydroxylamines and 4-Hydroxyalkyl-1, 2-oxazetidines

V Capriati, S Florio, R Luisi, A Salomone…

Index: Luisi, Renzo; Capriati, Vito; Florio, Saverio; Vista, Teresa Journal of Organic Chemistry, 2003 , vol. 68, # 25 p. 9861 - 9864

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Citation Number: 16

Abstract

A simple and efficient stereoselective synthesis of polysubstituted β, γ-epoxyhydroxylamines and 4-hydroxyalkyl-1, 2-oxazetidines, based on the addition of α-lithiated aryloxiranes to nitrones and subsequent cyclization of the corresponding intermediates in a 4-exo-tet mode,