An improved large scale synthesis of 2-amino-4-chloropyridine and its use for the convenient preparation of various polychlorinated 2-aminopyridines

KS Gudmundsson, JM Hinkley, MS Brieger…

Index: Synthetic Communications, , vol. 27, # 5 p. 861 - 870

Full Text: HTML

Citation Number: 11

Abstract

Page 1. SYNTHETIC COMMUNICATIONS, 27(5), 861-870 (1997) ... A retrosynthetic analysis revealed that 4, 5 and 6 could be obtained from a ... overall yield of 55 % in five steps8 However this lengthy preparation appeared unsuitable for a large scale preparation. ...