Synthesis of 1, 1-difluoroethylsilanes and their application for the introduction of the 1, 1-difluoroethyl group

R Mogi, K Morisaki, J Hu, GKS Prakash…

Index: Mogi, Ryo; Morisaki, Kazuo; Hu, Jinbo; Prakash, G.K. Surya; Olah, George A. Journal of Fluorine Chemistry, 2007 , vol. 128, # 10 p. 1098 - 1103

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Citation Number: 14

Abstract

1, 1-Difluoroethysilanes (R3SiCF2CH3, R= Me or Et) were synthesized from 1, 1- difluoroethyl phenyl sulfone and chlorosilanes using magnesium metal via reductive 1, 1- difluoroethylation. It was confirmed that 1, 1-difluoroethylsilanes were effective 1, 1- difluoroethylating reagents for carbonyl compounds.

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