Enantioselective formation of quaternary stereocenters using the catalytic intramolecular Stetter reaction

JL Moore, MS Kerr, T Rovis

Index: Moore, Jennifer L.; Kerr, Mark S.; Rovis, Tomislav Tetrahedron, 2006 , vol. 62, # 49 p. 11477 - 11482

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Citation Number: 58

Abstract

Catalytic carbon–carbon bond formation resulting in the creation of a quaternary stereocenter is a useful but challenging tool in organic chemistry. 1, 1a, 1b and 1c In addition to established approaches using chiral auxiliaries, 2, 2a and 2b significant progress has been made in recent years aimed at catalytic methods for the formation of quaternary stereocenters. These include the intramolecular Heck reaction, 3 rearrangement of enol carbonates, 4, 4a and 4b ...