Preparation of phenylethylbenzamide derivatives as modulators of DNMT3 activity

A Kabro, H Lachance, I Marcoux-Archambault…

Index: MedChemComm, , vol. 4, # 12 p. 1562 - 1570

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Citation Number: 7

Abstract

... as H3), activator peptide (3.6 μM) and 200 nM 3 H-SAM in a total volume of 25 ... Samples were incubated (37 °C, 4 h) and then heat inactivated (80 °C, 20 min ... Many other epigenetic enzymes are also currently being explored as potential target for the development of therapeutic ...