Synthesis of Small Combinatorial Libraries of Natural Products: Identification and Quantification of New Long??chain 3??Methyl??2??alkanones from the Root Essential Oil …

NS Radulović, MS Denić…

Index: Radulovic, Niko S.; Denic, Marija S.; Stojanovic-Radic, Zorica Z. Phytochemical Analysis, 2014 , vol. 25, # 1 p. 75 - 80

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Citation Number: 6

Abstract

Objective To identify nine new constituents (long-chain 3-methyl-2-alkanones) from a fraction of this root essential oil with a low minimum inhibitory concentration value (0.8 µg/mL) by employing a synthetic methodology that leads to the formation of a small combinatorial library of these compounds. Methods The identity of these constituents was inferred from mass spectral fragmentation patterns and GC retention data. A library of 3- ...