4-{(2R)-[3-Aminopropionylamido]-3-(2, 4-dichlorophenyl) propionyl}-1-{2-[(2-thienyl) ethylaminomethyl] phenyl} piperazine as a Potent and Selective Melanocortin-4 …

C Chen, J Pontillo, BA Fleck, Y Gao…

Index: Journal of Medicinal Chemistry, , vol. 47, # 27 p. 6821 - 6830

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Citation Number: 33

Abstract

... Journal of Medicinal Chemistry. ... 2 Although many of them are considered to be drug targets, GPCRs activated by peptides and proteins, 3 due to a lack of structural information, have been particularly challenging to medicinal chemists to design non-peptide small-molecule ...