Palladium??Catalyzed Carbonylative Synthesis of Quinazolinones from 2??Aminobenzamide and Aryl Bromides
…, L He, H Neumann, M Beller
Index: Wu, Xiao-Feng; He, Lin; Neumann, Helfried; Beller, Matthias Chemistry - A European Journal, 2013 , vol. 19, # 38 p. 12635 - 12638
Full Text: HTML
Citation Number: 0
Abstract
2-Aryl quinazolin-4 (3H)-one (quinazolinone) is a naturally occurring class of heterocycles which can exhibit a wide range of biological activities (Scheme1). Their reported properties included anticancer, antiviral, anti-inflammatory, anti-microbial activity among others [1] Additionally, quinazolinones are used as ligands for benzodiazepine and AMPA receptors in the CNS system or as DNA binders.[2] Because of their importance, many useful synthetic ...
Related Articles:
[Chandrika, P. Mani; Yakaiah; Rao, A. Raghu Ram; Narsaiah; Reddy, N. Chakra; Sridhar; Rao, J. Venkateshwara European Journal of Medicinal Chemistry, 2008 , vol. 43, # 4 p. 846 - 852]
Identification of chemokine receptor CCR4 antagonist
[Purandare, Ashok V.; Gao, Aiming; Wan, Honghe; Somerville, John; Burke, Christine; Seachord, Carrie; Vaccaro, Wayne; Wityak, John; Poss, Michael A. Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 10 p. 2669 - 2672]
[Hradil, Pavel; Grepl, Martin; Hlavac, Jan; Lycka, Antonin Heterocycles, 2007 , vol. 71, # 2 p. 269 - 280]
[Hradil, Pavel; Grepl, Martin; Hlavac, Jan; Lycka, Antonin Heterocycles, 2007 , vol. 71, # 2 p. 269 - 280]