Synthesis of hydroxybenzaldehyde derivatives containing an isoxazole heteroring
…, EA Dikusar, SK Petkevich, NA Zhukovskaya…
Index: Potkin; Gadzhily; Dikusar; Petkevich; Zhukovskaya; Aliev; Nagieva Russian Journal of Organic Chemistry, 2012 , vol. 48, # 1 p. 127 - 136
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Citation Number: 5
Abstract
Abstract 5-Phenyl (p-tolyl) isoxazole-3-carboxylic acids were synthesized starting from 3- hydroxyiminomethyl-5-phenyl (p-tolyl) isoxazoles, and their reactions with p- hydroxybenzaldehyde, vanillin, isovanillin, o-vanillin, and ethyl vanillin gave the corresponding esters. The latter were brought into condensation with aromatic amines to obtain Schiff bases which were reduced to amines.
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