Structure-Based Design of Novel 2-Amino-6-phenyl-pyrimido [5′, 4′: 5, 6] pyrimido [1, 2-a] benzimidazol-5 (6 H)-ones as Potent and Orally Active Inhibitors of …

MW Martin, J Newcomb, JJ Nunes…

Index: Journal of Medicinal Chemistry, , vol. 51, # 6 p. 1637 - 1648

Full Text: HTML

Citation Number: 37

Abstract

... Journal of ... Chem. , 2008, 51 (6), pp 1637–1648. DOI: 10.1021/jm701095m. Publication Date (Web): February 16, 2008. Copyright © 2008 American Chemical Society. * To whom correspondence should be addressed: Tel.: 617-444-5013 . ... Department of Medicinal Chemistry. , ‡ ...

Related Articles:

Design, synthesis and biological activities of Nilotinib derivates as antitumor agents

[Bioorganic and Medicinal Chemistry, , vol. 21, # 9 p. 2527 - 2534]

Benzophenone derivatives: a novel series of potent and selective inhibitors of human immunodeficiency virus type 1 reverse transcriptase

[Journal of Medicinal Chemistry, , vol. 38, # 10 p. 1657 - 1665]

Novel 2-aminopyrimidine carbamates as potent and orally active inhibitors of Lck: synthesis, SAR, and in vivo antiinflammatory activity

[Journal of Medicinal Chemistry, , vol. 49, # 16 p. 4981 - 4991]

Potential antidepressants. Synthesis of 6, 11-dihydrodibenzo [b, e] thiepin-11-yl (dimethylaminomethyl) phenyl ethers, sulfides, amines and some related compounds

[Sindelar, Karel; Valenta, Vladimir; Holubek, Jiri; Matousova, Oluse; Protiva, Miroslav Collection of Czechoslovak Chemical Communications, 1990 , vol. 55, # 1 p. 282 - 295]

More Articles...