Synthesis and characterisation of new types of side chain cholesteryl polymers

B Wang, H Du, J Zhang

Index: Wang, Bin; Du, Haiyan; Zhang, Junhua Steroids, 2011 , vol. 76, # 1-2 p. 204 - 209

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Citation Number: 26

Abstract

A series of cholesterol derivatives have been synthesised via the alkylation reaction of the 3- hydroxyl group with the aliphatic bromide compounds with different chain lengths, namely 3β-alkyloxy-cholesterol. The double bond between the C5 and C6 positions in these cholesterol derivatives was oxidised into epoxy, followed by an epoxy-ring-opening reaction with the treatment with acrylic acid, resulting in a series of 3β-alkyloxy-5α-hydroxy-6β- ...