Development of an enabling route to PF-00610355: a novel inhaled β2-adrenoreceptor agonist
PD de Koning, IR Gladwell, IB Moses…
Index: Huang, Ling; Liu, Juntao; Shan, Wenjun; Liu, Bao; Shi, Anding; Li, Xingshu Chirality, 2010 , vol. 22, # 2 p. 206 - 211
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Citation Number: 5
Abstract
... 21) mixture with Et 3 N(HF) 3 to affect complete deprotection, affording amino alcohol 22. ... Partially purified 8 was isolated after concentration to half volume and crystallization at 20 °C. A ... Effective synthetic routes to two of the key building blocks, chiral bromide 1 and amine 6, are ...
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