Chemistry of Natural Compounds

Improved methods of obtaining Nim-trityl-substituted histidine derivatives

VF Pozdnev

Index: Pozdnev, V. F. Chemistry of Natural Compounds, 1982 , vol. 18, # 3 p. 322 - 327 Khimiya Prirodnykh Soedinenii, 1982 , # 3 p. 349 - 354

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Abstract

Abstract Two variants are proposed for the synthesis of N α-Boc-N im-tritylhistidiine. The first variant starts from N α, N im-di-Boc-histidine, from which the N im-Boc group is removed with hydrazine hydrate. The N α-Boc-histidine formed is esterified with chlorotrimethylsilane,

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