Synthesis and antiviral activity of 4-benzyl pyridinone derivatives as potent and selective non-nucleoside human immunodeficiency virus type 1 reverse transcriptase …

…, M Ventura, L Tarrago-Litvak, E Bisagni

Index: Bisagni, Emile; Rautureau, Marilys; Huel, Christiane Heterocycles, 1988 , vol. 27, # 7 p. 1671 - 1678

Full Text: HTML

Citation Number: 32

Abstract

Several 4-benzyl analogues of 5-ethyl-6-methyl-4-(phenylthio) pyridin-2 (1 H)-ones were synthesized and evaluated for their anti-HIV-l activities. Key transformations include metalation at the 4-C-position of 5-ethyl-2-methoxy-6-methyl-3-pivaloylaminopyridine (5)

Related Articles:

INDQ/NO, a bioreductively activated nitric oxide prodrug

[Sharma, Kavita; Iyer, Aishwarya; Sengupta, Kundan; Chakrapani, Harinath Organic Letters, 2013 , vol. 15, # 11 p. 2636 - 2639]

Intramolekulare Aromatenalkylierungen, 22. Mitt. Synthese von cis??1, 6, 10??Trimethyl??1, 2, 3, 4, 5, 6, 7, 8, 9, 10??decahydroindolo (4, 3??fg) chinolin, ein neuer Zugang …

[Reimann; Hargasser Archiv der Pharmazie, 1988 , vol. 321, # 11 p. 823 - 826]

The Copper??Catalyzed C??3??Formylation of Indole C H Bonds using Tertiary Amines and Molecular Oxygen

[Chen, Jianbin; Liu, Bin; Liu, Dongfang; Liu, Shan; Cheng, Jiang Advanced Synthesis and Catalysis, 2012 , vol. 354, # 13 p. 2438 - 2442]

INDQ/NO, a bioreductively activated nitric oxide prodrug

[Sharma, Kavita; Iyer, Aishwarya; Sengupta, Kundan; Chakrapani, Harinath Organic Letters, 2013 , vol. 15, # 11 p. 2636 - 2639]

Eco-friendly synthesis and antimicrobial activities of substituted-5-(1H-indol-3-yl) methylene)-2, 2-dimethyl-1, 3-dioxane-4, 6-dione derivatives

[Thirupathi; Venkatanarayana; Dubey; Bharathi Kumari Medicinal Chemistry Research, 2014 , vol. 23, # 3 p. 1569 - 1580]

More Articles...