The design and synthesis of novel IBiox N-heterocyclic carbene ligands derived from substituted amino-indanols

JN Levy, CM Latham, L Roisin, N Kandziora…

Index: Levy, Jean-Noel; Latham, Christopher M.; Roisin, Loic; Kandziora, Nadine; Fruscia, Paolo Di; White, Andrew J. P.; Woodward, Simon; Fuchter, Matthew J. Organic and Biomolecular Chemistry, 2012 , vol. 10, # 3 p. 512 - 515

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Citation Number: 13

Abstract

A synthetic route towards a number of novel IBiox N-heterocyclic carbene (NHC) ligands has been developed. The resulting ligands have restricted flexibility and high steric demand. Preliminary studies have shown these ligands to give high levels of asymmetric induction in the copper-free allylic alkylation of cinnamyl bromide.

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