Synthesis of Chromones through LiOtBu/Air??Mediated Oxidation and Regioselective Cyclization of o??Hydroxyphenyl Propargyl Carbinols
…, C Wan, Q Wang, B Zhang, L Gao, Z Zha…
Index: Zhang, Shuai; Wan, Changfeng; Wang, Qiang; Zhang, Baiqun; Gao, Lingfeng; Zha, Zhenggen; Wang, Zhiyong European Journal of Organic Chemistry, 2013 , # 11 p. 2080 - 2083
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Citation Number: 8
Abstract
Abstract A cascade oxidative cyclization reaction for the synthesis of chromone derivatives was developed by using LiOtBu as a mediator and air as an oxidant. The reaction was carried out without the assistance of a transition metal under mild conditions to afford the chromones in good yields with high regioselectivities.
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