Reaction of Alkyl Halides with Mercury (II) Salts in Tetrahydrofuran. A Facile Preparation of 4-Alkoxybutyl Acetates and Chlorides

N Watanabe, S Uemura, M Okano

Index: Watanabe,N. et al. Bulletin of the Chemical Society of Japan, 1976 , vol. 49, p. 2500 - 2502

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Citation Number: 2

Abstract

The reaction of primary and secondary alkyl iodides and bromides with Hg (OAc) 2 and HgCl 2 in tetrahydrofuran (THF) affords the THF-incorporated compounds (1), RO (CH 2) 4 X [X= OAc and Cl, respectively], in good yields. When HgBr 2 and aqueous or alcoholic Hg (ClO 4) 2 were used as mercury (II) salts, the yields of 1 (X= Br, OH, and OR′) were low. Similar treatment with HgI 2 gave scarcely any 1. A reaction scheme which involves O- ...