Novel 5-hydroxytryptamine (5-HT3) receptor antagonists. I. Synthesis and structure-activity relationships of conformationally restricted fused imidazole derivatives.

M OHTA, T SUZUKI, T KOIDE, A MATSUHISA…

Index: Chemical and Pharmaceutical Bulletin, , vol. 44, # 5 p. 991 - 999

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Citation Number: 18

Abstract

... 1996 Pharmaceutical Society of Japan NIT—Electronic Library Service ... Chemistry The syntheses of the compounds 6, 9, 11, 12 and IFZI (Table 1) are outlined in Chart 3 ... 2-methoxypheny1)ureas 11 and 12 were prepared by the addition of 4-(N—methylamino)methyl—5— Vol. ...