Reactions of heterocumulenes with organometallic reagents: XII. Reaction of metallated vinyl ethers with isocyanates: Ingenious synthesis of pyruvic acid amides
NA Nedolya, NI Shlyakhtina
Index: Nedolya; Shlyakhtina Russian Journal of Organic Chemistry, 2007 , vol. 43, # 8 p. 1124 - 1129
Full Text: HTML
Citation Number: 2
Abstract
Abstract Acid hydrolysis of 2-alkoxy-N-substituted acrylamides easily obtained by reacting α- metallated vinyl ethers with isocyanates proceeded regiospecifically leading to the formation in a high yield of virtually undescribed and difficultly available 2-oxo-N-substituted propanamides.
Related Articles:
Phosphoenol pyruvamides. Amide-phosphate interactions in analogs of phosphoenol pyruvate
[Kluger, Ronald; Chow, Jane Frances; Croke, James J. Journal of the American Chemical Society, 1984 , vol. 106, # 14 p. 4017 - 4020]
[Young,P.R. et al. Journal of the American Chemical Society, 1975 , vol. 97, p. 6544 - 6551]